the old masters of photography or painting would put objects in the centre to symbolize staticity, immobility, balance. but for movement, they would use one of the points of the principle of thirds, imaginary triangle, or vanishing points.
so, yes, if you want to say, i am going nowhere ( a man with a broken down car). or time is standing still (a broken clock). BANG U R DEAD (barrel of a gun ), Uncle Sam want YOU . all dead on centre.
yes..that's where you want to place it.