It's been a few weeks and maybe I've calmed down enough to try submitting some more isolated objects to IS. I have a nice new bunch for them to reject, and I'm building a collection of "too feathered or too rough" rejection emails.
This set is of a collection of objects and could either be one very large image or a series of smaller images which can be tiled if desired. It's not a bunch of 'similar' shots of the same thing - each individual image stands alone and contains different objects. If I combine them, the buyer won't get as much resolution.
Yes, I know that whichever way I go, they'll reject it and want it the other way. And when I do that, they'll say it contains artifacts. But, I have to try. 
What is IS's position on sets like this?
I don't have many problems with istock reviews lately, I think most of the time they get it right. I used to get more rejections before changing my screen, now I can see if there are any artifacts or other problems. Sometimes I get a reviewer that finds problems that just aren't there but that's rare.