I usually don't complain about rejects on IS; but, I had one the other day that has me wondering what next.  Mentioned it on the iS forum, but no response.

A few weeks back, I submitted an image of a woman jumping in an open field with a row of trees in the background.  Image was accepted, no problem.  A bit later, I thought the image may do better if the woman were completely isolated from the background.  Erased the background and resubmitted (nothing done to the woman's image, all work in TIFF).  Came back rejected as too soft.  OK, I can live with that.  Reduced the image (originally 11 mp) to 4 mp and resubmitted again.  You guessed it, rejected for being over sharpened (camera sharpening zero, RAW conversion sharpening zero, and no sharpening in post processing).  Besides, it had just been rejected for being too soft.

OK, now I have an image of a woman that is too soft, too sharp and just right.  I'm feeling like Goldilocks and IS is the three bears.  I could submit this to Scout, but I'd like a reply somewhere in my lifetime.  I could make an image in-between 11 and 4 mp and see if that's "just right", but who knows.  Or I could forget the whole thing as the image is selling elsewhere.

Any thoughts and/or suggestions?

I never heard an image is to sharp. sharp sounds good  . Maybe the mean your isolation.
When you downsized it to 4MP, the edges became too sharp and not smooth enough anymore?

well this may very well be a good example of different reviewers and how fine a line things get sliced on.  Some thing it is too sharp, some not sharp enough.. i suppose it IS somewhat personal opinion or different opinions of what Istock is looking for.  If i were you I would just try uplaoding it again if i wanted it in. 

I don't really think it is good practise to keep resubmitting the same shot, but in this case where you have gotten two different opinions on the same shot which are opposite eachother, i think that may be the only option.

Here's my strange rejection at iStockphoto(Stockxpert accepted it):

http://stockxpert.com/browse.phtml?f=view&id=3109461

Apparently, this requires a model release. I know it's some type of mistake, and I emailed support about it(a week ago, still no response). Personally, I like iStockphoto the best out of all the agencies so far. But this rejection was ... interesting. 

Of course you need a model release.  That's the invisible man behind those glasses.  Don't you see him?   

Erm ... sorry ... I think I got confused between all these rejections ... *blush*